The past two decades have seen extraordinary advances in our understanding of the role of the pulmonary epithelium in airway health and disease. Our understanding of epithelial biology has expanded exponentially in the past decade. This book provides a unique comprehensive description of the structure of the epithelium, its damage by various agents and the mechanism of epithelial repair. In addition, it´s detailed coverage includes not only the multiple ways in which the epithelium contributes to host defence, but also the nature and functional consequences of the interactions of inhaled pathogens, including viruses, bacteria, allergens and pollutants. the role of the epithelium in regulating airway inflammation and structure is also discussed, as is the role of the epithelium as a target for inhaled medications and as a route for novel drug delivery. Containing chapters on multiple aspects of epithelial function in health and disease, each one is written by a leader in the field. This is essential reading for pulmonary researchers and physicians requiring detailed advanced understanding of the epithelium as well as those working in allergy, biomedical and pharmaceutical research.
The home candy maker´s guide to creating stunning chocolates and confections Chocolates and Confections at Home offers detailed expertise for anyone who wants to make truly amazing homemade confections and candies. The Culinary Institute of America and baking and pastry arts professor Peter Greweling provide recipes and step-by-step techniques that make even the most ambitious treats simple for any home cook. In addition, Chocolates and Confections at Home includes ingredient and equipment information, packaging and storage practices, and troubleshooting tips for common preparation issues. Richly illustrated with more than 150 full-color photos that illustrate key techniques as well as finished confections Covers chocolates, truffles, toffees and taffies, fudge and pralines, marshmallows, jellies, nuts, and much more Author Peter Greweling is a professor of baking and pastry arts at the CIA, as well as a Certified Master Baker and Certified Hospitality Educator Chocolates and Confections at Home is the ideal resource for anyone who wants to graduate from chocolate chip cookies to create impressively decadent delights.
The definitive interdisciplinary reference work for wound ballistics Fundamentals in Physics, arms and ammunition, ballistics Simulating gunshot wounds: Virtopsy – a virtual autopsy method, combining CT, MRT and surface scanning and Materials that reproduce the interaction of soft tissue, bone and blood vessels with a bullet that penetrates the body. Wound ballistics for Short-range and long-range weapons, fragments, such as those from bombs and hand grenades, gas jets from blanks, gas weapons, etc., ´´Non-lethal” weapons as used by the police, in military operations or in urban settings Specialist knowledge and reference detailed tables: ballistic tables for typical ammunition, ballistic values for numerous types of ammunition, including older types, materials properties, plus additional, hard-to-find data. Most tables are in both metric and U.S. units., an extensive trilingual glossary of specialized terminology in German, English and French NEW: the latest diagnostic / simulation methods and the latest types of ammunition The practice and application of wound ballistics in: forensic medicine, surgery – especially emergency and war surgery and international conventions Globalized conflict zones, terrorism and crime – these issues affect a wider circle than just the armed forces and medical services abroad. Police officers, surgeons, forensics specialists and criminalists also need to be familiar with ballistics and gunshot wounds and must be able to assess the complex factors involved. The practice and application of wound ballistics in forensic medicine. surgery – especially emergency and war surgery and International conventions. Globalized conflict zones, terrorism and crime – these issues affect a wider circle than just the armed forces and medical services abroad. Police officers, surgeons, forensics specialists and criminalists also need to be familiar with ballistics and gunshot wounds and must be able to assess the complex factors involved.
The world´s only annual publication devoted to the study of the laws of armed conflict, the Yearbook of International Humanitarian Law provides a truly international forum for high-quality, peer-reviewed academic articles focusing on this highly topical branch of international law. Ease of use of the Yearbook is guaranteed by the inclusion of a detailed index. Distinguished by its topicality and contemporary relevance, the Yearbook of International Humanitarian Law bridges the gap between theory and practice and serves as a useful reference tool for scholars, practitioners, military personnel, civil servants, diplomats, human rights workers and students.
Diseases of Poultry is the most comprehensive reference for all aspects of poultry health and diseases, including pathogenesis, diagnostics, epidemiology, and control methods. Published in partnership with the American Association of Avian Pathologists, the Thirteenth Edition remains the international definitive reference, adding newer diagnostic methods and a new chapter on the emerging importance of zoonotic infections for poultry pathogens. Other updates include new high-quality photographs, additional discussion of conceptual operational biosecurity and disease control in organic production systems, and a greater emphasis throughout on the differences in disease incidence and treatments for the United States and other areas around the globe. Organized logically by disease type, the book offers detailed coverage of the history, etiology, pathobiology, diagnosis, and intervention strategies, as well as the economic and public health significance, for an exhaustive list of common and uncommon diseases. Diseases of Poultry, 13th Edition is an essential purchase for poultry veterinarians, veterinary diagnosticians, poultry scientists, students specializing in poultry health, and government officials who deal with poultry health in regulatory climate.
The legal consequence of the superior orders defense has long been debated as one of the major problems in international criminal law. Several controversial issues such as the immunity of the state, the absolute character of military discipline, and immunity on the grounds of mistake of law and/or coercion have been complexly interwoven in the debates. The Execution of Illegal Orders and International Criminal Responsibility provides a comprehensive portrait of the relevant debates at the international level up to the present, analyzes the conflicting views, and shows the significance of the development of international rules for the superior orders defense as well as the implication of the fact that issues concerning some detailed or related rules have been left unresolved. This study presents to present a new standpoint not only on dealing with the problem of the superior orders defense but also on reconsidering the international stipulation of rulemaking with regard to criminal matters.
Presenting an area of research that intersects with and integrates diverse disciplines, including molecular biology, applied informatics, and statistics, among others, Bioinformatics for Omics Data: Methods and Protocols collects contributions from expert researchers in order to provide practical guidelines to this complex study. Divided into three convenient sections, this detailed volume covers central analysis strategies, standardization and data-management guidelines, and fundamental statistics for analyzing Omics profiles, followed by a section on bioinformatics approaches for specific Omics tracks, spanning genome, transcriptome, proteome, and metabolome levels, as well as an assortment of examples of integrated Omics bioinformatics applications, complemented by case studies on biomarker and target identification in the context of human disease. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.
This well-received book, now in its fifth edition, is unique in providing a detailed examination of the technological basis of radiation therapy. Another unique feature is that the chapters are jointly written by North American and European authors. This considerably broadens the book’s contents and increases its applicability in daily practice throughout the world. The book is divided into two sections. The first section covers basic concepts in treatment planning and explains the various approaches to radiation therapy, such as intensity-modulated radiation therapy, tomotherapy, stereotactic radiotherapy, and high and low dose rate brachytherapy. The second discusses in depth the practical clinical applications of the different radiation therapy techniques in a wide range of cancer sites. All chapters have been written by leaders in the field. This book will serve to instruct and acquaint teachers, students, and practitioners with the basic technological factors and approaches in radiation therapy.
An area in the midst of deep change, Southern Africa was in turmoil a short decade ago, its politics framed by white versus black, colonialism versus decolonialism, majority rule versus minority rights. With new political discourses beginning in the early 1990s, the mood today is one of interdependencies between the SADC member countries. To enhance one´s understanding of the area, this book provides a comprehensive guide to the history of Southern Africa since the demise of colonialism. In detailed chronologies, it traces the history of the twelve developing Southern African countries-Angola, Botswana, Lesotho, Malawi, Mauritius, Mozambique, Namibia, South Africa, Swaziland, Tanzania, Zambia, and Zimbabwe. Bringing together information on the political development of the SADC member countries, the book aims to provide easy access to the information. The detailed chronologies show the political events as they unfolded, while the two indexes provide easy access to the events. The book is a useful guide to key developments, the role played by political parties, treaty information, and individual personalities.
Vital to academic researchers, the medical field, and especially to biotech and pharmaceutical scientists, metabolomics is a rapidly expanding field that will provide a key link between functional biology (phenotypes) and the inner workings of cells in tissues or whole organisms. In The Handbook of Metabolomics, expert researchers provide readers with the current state of metabolomic development and the integration of metabolomics with transcriptomics and proteomics, illustrated by research efforts related to toxicology and pharmacology. The detailed contributions deal with topics ranging from sample preparation and considerations, both laboratory and clinical, analytical methodologies for metabolite and isotopomer profiling, metabolic flux modeling, database construction, and the integration of ‘omics for systems biochemical understanding, amongst other topics.