Detailed Genetic Analysis of a Wide Faba Bean (Vicia faba L.) Cross German x Moroccan: Memen Surahman
Detailed Genetic Analysis of a Wide Faba Bean (Vicia faba L.) Cross ”German x Moroccan“:
Detailed Genetic Analysis of a Wide Faba Been Cross German x Moroccan:Genetic Map of Faba Bean Memen Surahman, Wolfgang Link
With the continuing advances in sequencing technologies and the availability of thousands of distinct human genomes, we are fast approaching the day when ´´personal genomes´´ become a standard study measure and a routine component of personal health records. In Genetic Variation: Methods and Protocols , expert researchers address the rising importance of genome variation, both at the level of the individual and in population-based studies of disease, with a collection of detailed protocols reflecting the nature and impact of genetic variation on human phenotypes. The contributions cover a majority of the most important forms of genetic variation studied today, including single nucleotide polymorphisms (SNPs), insertions/deletion (indels), copy number variation (CNVs), variable number tandem repeats (VNTRs), mitochondrial variation, mobile elements, and epigenetic variation. As a volume in the highly successful Methods in Molecular Biology (TM) series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Convenient and cutting-edge, Genetic Variation: Methods and Protocols aims to bring bench scientists, clinicians, and bioinformaticians together in order to aid progress toward a greater understanding of the full impact of variation on human health and disease. ´´Your genome is an email attachment´´ What a difference a few years can make? In 2001, to a global fanfare, the completion of the frst draft sequence of the human genome was announced. This had been a Herculean effort, involving thousands of researchers and millions of dollars. Today, a project to re-sequence 1,000 genomes is well underway, and within a year or two, your own ´´personal genome´´ is likely to be available for a few thousand pounds, a price that will undoubtedly decrease further. We are fast approaching the day when your genome will be available as an email attachment (about 4 Mb). The key to this feat is the fact that any two human genomes are more than 99% identical, so rather than representing every base, there is really only a requirement to store the 1% of variable sequence judged against a common reference genome. This brings us directly to the focus of this edition of Methods in Molecular Biology, Genetic Variation. The human genome was once the focus of biology, but now individual genome var- tion is taking the center stage. This new focus on individual variation ultimately democ- tizes biology, offering individuals insight into their own phenotype. But these advances also raise huge concerns of data misuse, misinterpretation, and misunderstanding. The immediacy of individual genomes also serves to highlight our relative ignorance of human genetic variation, underlining the need for more studies of the nature and impact of genetic variation on human phenotypes.
The adult patient diagnosed with or at risk for a neurogenetic disease has many questions and concerns for the genetic counselor, the neurologist, and other practitioners. Because of the emotional and potentially life-altering impact of these diseases on the patient and family, counseling can be especially challenging. A rare hands-on guide to the subject, Genetic Counseling for Adult Neurogenetic Disease deals with core issues that differentiate adult neurogenetic counseling from its more familiar pediatric counterpart. This innovative book with accompanying videos is designed to fill in deficits in this area typical of training programs in genetic counseling (which have pediatrics and prenatal concentrations) and neurology (which rarely cover genetic counseling). For each condition featured, chapters include a detailed overview of genetic symptoms, diagnostic criteria, and management, plus guidelines for asking, and answering, pertinent questions. The major concentration, however, is on genetic counseling issues and case histories illustrating these issues. As an added dimension, the accompanying videos depict representative issues and challenges in genetic counseling for specific diseases in addition to the basics of a neurological examination. Among the conditions discussed: Movement disorders, including Parkinson´s disease. Dementias, including Alzheimer´s disease. Stroke. Motor neuron diseases. Neuropathies and channelopathies. Adult muscular dystrophies. Neurocutaneous syndromes. Plus a section on neurological and neuropsychological evaluation. This is information that will stay relevant as technologies change and genetic understanding evolves. Genetic Counseling for Adult Neurogenetic Disease offers advanced clinical wisdom for genetic counselors as well as neurologists, neuropsychologists, and other referring clinicians.
Travelling Salesman Problem(TSP)optimization through Genetic Algorithm:Improvised solution to VLSI Detailed Routing and National Tour Dr. R. Geetha Ramani, R. Geetha Ramani
Genetics of Hearing Loss in Southern Egyptian Population:A Detailed Genetic Analysis Of Non-Syndromic And Syndromic Hearing Loss In Southern Egypt Governorates Mostafa Mohamed
Secunmir Personality Test:New personality test based on psycho-genetic researches, detailed description of non-accentuated and accentuated traits Neli Feldman
Like its preceding editions, this atlas is an indispensable guide to the field of neurology, featuring the most clinically essential images and figures. Chapters offer insight and research written by deeply practiced, knowledgeable neurologists that is supplemented with detailed imagery, tables, algorithms, and delineative drawings. Topics covered include developmental and genetic diseases, neuroendocrine disorders, critical care neurology, cerebrovascular disease, dementias, behavioral neurology, neuro-oncology, movement disorders, epilepsy, neuromuscular diseases, infectious diseases, neuroimmunology, neurotoxic disorders, and headache. The authors also delve into specific issues currently prevalent in neuroscientific research, including Alzheimer´s disease, dementia, Machado-Joseph disease, Huntington´s disease, and brain scanning with PET and fMRI. The Atlas of Clinical Neurology, 4th Edition serves as a comprehensive and premier visual resource for neurologists.
This grammar is a first detailed description of Qaqet, a non-Austronesian language spoken in the mountainous interior of East New Britain Province, Papua New Guinea. Qaqet belongs to the small Baining language family (comprising six languages), but its wider genetic affiliations remain unclear. It is included among the geographically-defined East Papuan languages. The grammar presents a synchronic description of the language. From a language family perspective, the Baining languages are structurally fairly similar, but there are considerable differences in detail that point to different language-internal developments and grammaticalization paths. From an East Papuan and areal perspective, Qaqet exhibits both typical East Papuan features (e.g., nominal classification, possessor/possessed order, highly compositional lexicon) as well as areal features (e.g., AVO ~ SV constituent order, articles and determiners, prepositions). The description is based on primary data collected during fieldwork (from 2011 onwards), including both natural and elicited data. The description thereby provides new analyses and insights that are relevant to our understanding of the genetic and areal relationships in this region.